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This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

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This concise, practical handbook discusses EGFR mutations in NSCLC, testing methods and technology, current and emerging therapies, and resources. It offers readers a fast synopsis of key studies and available treatment options.

This concise, practical handbook discusses EGFR mutations in NSCLC, testing methods and technology, current and emerging therapies, and resources. It offers readers a fast synopsis of key studies and available treatment options.

Book is in NEW condition. 0.62

Acceptable/Fair condition. Book is worn, but the pages are complete, and the text is legible. Has wear to binding and pages, may be ex-library. 1.1

Book is in Used-VeryGood condition. Pages and cover are clean and intact. Used items may not include supplementary materials such as CDs or access codes. May show signs of minor shelf wear and contain very limited notes and highlighting. 0.62

Book is in NEW condition. 0.84

Book is in Used-Good condition. Pages and cover are clean and intact. Used items may not include supplementary materials such as CDs or access codes. May show signs of minor shelf wear and contain limited notes and highlighting. 0.84

A Comprehensive Guide for Patients and Practitioners Although evidence supporting the benefits of ketogenic diet therapies continues to mount, there is little to guide those who wish to adopt this diet as a metabolic therapy for cancer. Keto for Cancer fills this need. Inspired by the work of Dr. Thomas N. Seyfried, PhD, nutritionist Miriam Kalamian has written the first book to lay out comprehensive guidelines that specifically address the many challenges associated with cancer, and particularly the deep nutritional overhaul involved with the ketogenic diet. Kalamian, a leading voice in the keto movement, is driven by passion from her own experience in using the ketogenic diet for her young son. Her book addresses the nuts and bolts of adopting the diet, from deciding whether keto is the right choice to developing a personal plan for smoothly navigating the keto lifestyle. It is invaluable for both beginners and seasoned users of the ketogenic diet, as well as for health-care professionals who need a toolkit to implement this targeted metabolic therapy. The book guides readers to a deeper understanding of the therapeutic potential of the ketogenic diet―which extends well beyond simply starving cancer―emphasizing the powerful impact the diet has on the metabolism of cancer cells. Nutritional nuances are explored in sections such as “Fasting Protocols” and “Know What’s in the Foods You Eat” while meal templates and tracking tools are provided in “Preparing Keto Meals.” Kalamian also discusses important issues such as self-advocacy. Readers of Keto for Cancer are empowered to “get off the bench and get in the game.” To that end, Kalamian offers tips on how to critically examine cancer-care options then incorporate what resonates into a truly personalized treatment plan.

A Comprehensive Guide for Patients and Practitioners Although evidence supporting the benefits of ketogenic diet therapies continues to mount, there is little to guide those who wish to adopt this diet as a metabolic therapy for cancer. Keto for Cancer fills this need. Inspired by the work of Dr. Thomas N. Seyfried, PhD, nutritionist Miriam Kalamian has written the first book to lay out comprehensive guidelines that specifically address the many challenges associated with cancer, and particularly the deep nutritional overhaul involved with the ketogenic diet. Kalamian, a leading voice in the keto movement, is driven by passion from her own experience in using the ketogenic diet for her young son. Her book addresses the nuts and bolts of adopting the diet, from deciding whether keto is the right choice to developing a personal plan for smoothly navigating the keto lifestyle. It is invaluable for both beginners and seasoned users of the ketogenic diet, as well as for health-care professionals who need a toolkit to implement this targeted metabolic therapy. The book guides readers to a deeper understanding of the therapeutic potential of the ketogenic diet―which extends well beyond simply starving cancer―emphasizing the powerful impact the diet has on the metabolism of cancer cells. Nutritional nuances are explored in sections such as “Fasting Protocols” and “Know What’s in the Foods You Eat” while meal templates and tracking tools are provided in “Preparing Keto Meals.” Kalamian also discusses important issues such as self-advocacy. Readers of Keto for Cancer are empowered to “get off the bench and get in the game.” To that end, Kalamian offers tips on how to critically examine cancer-care options then incorporate what resonates into a truly personalized treatment plan.

Introducing the 10 muscle stimulator, a wireless dual-channel 10 machine pulse massager offering 12 modes and 40 intensity levels for versatile pain relief. With independent control channels CH1 and CH2, this device allows precise adjustments, making it ideal for targeted therapy on various body parts. Lightweight, portable, and featuring 4 sticky electrodes, it's a convenient solution for anyone seeking safe, drug-free pain relief and muscle stimulation on the go. Color: White.

Reusable gel pack can be heated in the microwave or frozen; Applies heat or cold therapy to help alleviate pain Hook and loop fasteners for the gel pack allow for targeted pain relief, providing adjustable compression to aid in recovery Helps reduce swelling and inflammation due to injury Soft, breathable materials for a comfortable wear and universal design can be used on foot, ankle, or even the elbow DESCRIPTION The PowerStep® Hot/Cold Therapy Wrap is the perfect addition to your RICE treatme

WHAT IT IS The Infini IQ Thermal Therapy Face & Body Device is a versatile tool designed for targeted results on both face and body. With its flat-head design, it effectively addresses complexion challenges while also providing relief for body aches and minor muscle and joint discomfort. Imported. FEATURES Red LED therapy Thermal therapy HOW TO USE IT Simply apply the device to areas of concern, press gently, and move in circular mo. Womens - Beauty > Saks Off 5th. Infini.

Dual compression anatomical design for enhanced pain relief, recovery and support Contoured support pad targeted to the arch & plantar fascia Ergonomic, lightweight design for all-workout comfort and fit Moisture-wicking, breathable fabric with 4-way stretch Left & right specific

Dual compression anatomical design for enhanced pain relief, recovery and support Contoured support pad targeted to the arch & plantar fascia Ergonomic, lightweight design for all-workout comfort and fit Moisture-wicking, breathable fabric with 4-way stretch Left & right specific

Dual compression anatomical design for enhanced pain relief, recovery and support Contoured support pad targeted to the arch & plantar fascia Ergonomic, lightweight design for all-workout comfort and fit Moisture-wicking, breathable fabric with 4-way stretch Left & right specific

Occupational Therapy Tools for Autism Spectrum Disorder is a hand book designed for use by Paediatric Occupational Therapists working with children and young people with Autism Spectrum Disorder. It is specifically targeted at newly qualified and junior occupational therapists working in paediatric occupational therapy but is also an easy to use reference for more experienced clinicians. It is based on current evidence and the culmination of the contributors extensive experience in assessing and treating children with Autism Spectrum Disorder.

Patients with personality disorders need targeted treatments which are able to deal with the specific aspects of the core pathology and to tackle the challenges they present to the treatment clinicians. Such patients, however, are often difficult to engage, are prone to ruptures in the therapeutic alliance, and have difficulty adhering to a manualized treatment. Giancarlo Dimaggio, Antonella Montano, Raffaele Popolo and Giampaolo Salvatore aim to change this, and have developed a practical and systematic manual for the clinician, using Metacognitive Interpersonal Therapy (MIT), and including detailed procedures for dealing with a range of personality disorders. The book is divided into two parts, Pathology, and Treatment, and provides precise instructions on how to move from the basic steps of forming an alliance, drafting a therapy contract and promoting self-reflections, to the more advanced steps of promoting change and helping the patient move toward health and adaptation. With clinical examples, summaries of therapies, and excerpts of session transcripts, Metacognitive Interpersonal Therapy for Personality Disorders will be welcomed by psychotherapists, clinical psychologists and other mental health professionals involved in the treatment of personality disorders.